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IVMED-80 (iVeena), which has received an orphan drug designation from the FDA. This drug has copper as an active ingredient, to enhance the activity of lysyl oxidase. Keratoconus occurs, Dr. Ambati explained, when there is a deficiency of natural crosslinks in the cornea, which is associated with lysyl oxidase mutations. Donor tissue that had been
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Keratoconus is a progressive disease of the outer transparent layer of the eye ball called the cornea affecting children and young adults. It is characterized by progressive weakening and thinning of the normally round cornea causing it to bulge forward and assume a cone like shape .This corneal steepening and irregularity results in the formation
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