Call us

+91-9240214610 (Bandra)
+91-9240214611 (Kandivali)

  • JAS-ANZ Accredited Certification
  • ICS Certified
  • NABH Certified Eye Hospital in Mumbai
Ojas Eye Hospital in Bandra, Kandivali, Mumbai

CAIRS Transplant

CAIRS Transplant

July 20, 2026

Corneal Allogenic Intrastromal Ring Segments is abbreviated as CAIRS. It is a minimally invasive eye surgery for keratoconus, pellucid marginal degeneration, and post-LASIK ectasia where small, arc-shaped pieces of human donor corneal tissue are inserted into channels in the middle layer of the patient’s cornea to flatten and reshape the bulge.

What Is The Purpose Of CAIRS?

CAIRS is used to treat keratoconus, correct irregular astigmatism, and flatten the cone-shaped bulge in a thinning cornea. It brings back clear vision and is safer than using artificial rings or full transplants.

  • Flattens the cornea: The procedure increases the volume of the outer edges of the cornea, flattening the abnormal cone shape.
  • Treats Ectasia: Treats progressive thinning of the cornea, such as keratoconus, pellucid marginal degeneration, and post-LASIK ectasia.
  • Enhances vision: Minimizes blur, ghosting, and distortion that standard glasses don’t handle as well.
  • Avoids transplants: Postpones or eliminates the need for a major full-thickness corneal graft.

Who is the right candidate for CAIRS?

Patients who have any of the following conditions are good candidates for the CAIRS procedure:

  • Moderate to advanced keratoconus (stages I to III).
  • Pellucid marginal degeneration or post-refractive surgery ectasia (post-LASIK or post-PRK).
  • Corneal steepness roughly between 50 and 70 diopters and a minimum safe stromal thickness (around 300 micrometers or more).
  • Has enough healthy underlying corneal tissue to support and respond to segment insertion.
  • Is free of extensive central corneal scarring that would otherwise demand a full corneal graft.
  • If there is difficulty or discomfort in wearing or fitting specialized rigid, scleral lenses.
  • People who want a minimally invasive, reversible option to postpone or avoid major corneal transplant surgery.
  • Patients with severe central corneal scarring, extreme corneal thinning, or active eye infections are not good candidates.

Is CAIRS a corneal transplant?

CAIRS is not a traditional full or partial corneal replacement transplant. Instead, it is a minimally invasive reshaping procedure that places small pieces of human donor corneal tissue into tiny tunnels in your own eye’s cornea to fix problems like keratoconus.

How Does the CAIRS Procedure Work?

The CAIRS technique involves implanting thin arcs of processed donor corneal tissue into small tunnels made within the weakened cornea of the patient to flatten the cone, regularize its shape, and improve vision. We present them below:

  • Mapping and planning: Doctors use 3D corneal scans to determine the exact depth, width, and arc length needed to alter the exact cone.
  • Anes­the­sia: Num­bing eye drops keep the pa­tient com­pletely com­fort­able dur­ing the brief, ap­prox­i­mate­ly 10-minute in-of­fice pro­ce­dure.
  • Tunnel creation: A precise femtosecond laser (or manual surgical instrument) cuts a delicate, sutureless mid-peripheral channel inside the corneal stroma.
  • Tissue insertion: Shaped segments cut from sterilized, donor human corneal stroma are gently threaded into the newly created tunnels using fine micro-instruments.
  • Stabilization: The added biological volume instantly flattens the irregular bulge. This is frequently combined with corneal cross-linking using riboflavin and UV light to lock the new shape permanently in place.

How Does CAIRS Improve Vision?

CAIRS improves vision by flattening and regularizing the shape of an irregular cone-shaped cornea. This is done by inserting thin strips of donor corneal stroma into precise pockets in the eye and adding tissue.

What are the benefits of CAIRS Transplant?

The full perks of CAIRS transplant include: 

  • Uses donor cornea tissue instead of hard plastic rings
  • Less risk of tissue extrusion or rejection.
  • Better tissue compatibility than synthetic rings and integrates smoothly into the host cornea without causing internal scarring.
  • Donor segments can be customized, edited, or even removed entirely if the patient’s needs change.
  • Takes about 15 minutes as a day-case procedure using only local numbing eye drops.
  • Involves no stitches and eliminates the long healing times associated with traditional full or partial-thickness corneal transplants.
  • Does not open the inner eye chamber, reducing the risk during the surgery compared to deep anterior lamellar keratoplasty (DALK).
  • Lowers irregular astigmatism to give sharper, clearer sight with glasses or soft contact lenses.
  • Helps many patients avoid or delay the need for a major corneal transplant procedure.

Can CAIRS Be Combined With Other Treatments?

Yes, CAIRS can be combined with other therapies, especially Corneal Cross-Linking (CXL) and future vision correction procedures such as ICL or laser procedures. Corneal Cross-Linking (CXL) is often used with CAIRS and stops the progression of keratoconus. CXL strengthens the weak cornea, and CAIRS helps the cornea to take shape to make vision sharp.

How Does Recovery After CAIRS Surgery Feel?

Recovery from CAIRS surgery is generally rapid and minimally invasive, with most patients returning to normal daily activities within 2 to 5 days. Mild discomfort, blurry vision, and a scratchy feeling typically resolve within a week, with full visual stabilization taking about 1 to 3 months. The cornea then remodels around the ring segments, causing vision to gradually clear and stabilize.

What are the risks and Possible Complications?

CAIRS surgery carries a low risk profile compared to traditional transplants. Very rare but possible post-operative complications include:

  • Infection
  • Inflammation
  • Segment displacement
  • Glare or halos
  • Under- or over-correction
  • Persistent visual symptoms
  • Need for additional treatment

How long do the results last?

CAIRS visual and structural results are designed to provide long-term stability, with clinical data showing parameters remain stable and maintained over multi-year follow-up periods. The longterm results are largely because they use human donor tissue, which is naturally incorporated into the cornea and so avoids the long term rejection, erosion, and thinning problems of older plastic implants.

Can keratoconus return after CAIRS?

Technically, keratoconus does not “grow back” after CAIRS, because the procedure is a reshaping method, not a cure. But without proper stabilization of the cornea, the condition underneath can still progress or continue to change, and that is when slight vision changes start to develop.

Is the surgery painful?

CAIRS surgery is generally not painful during the procedure, as it is performed using local or topical anesthetic eye drops. Most patients may feel mild pressure.

Will I still need glasses?

Yes, most people still need glasses or contact lenses after CAIRS, though vision and lens tolerance usually improve. The main goal of CAIRS is to reshape and regularize a cone-steeped or irregular cornea such as in keratoconus, so that light focuses better.

Can both eyes be treated?

Yes, both eyes can be treated with CAIRS if both eyes are showing signs of keratoconus or corneal ectasia. But doctors don’t usually treat the eyes at the same time, on the same day.

Final word

CAIRS is a new tissue-based treatment for selected keratoconus patients. It can improve corneal shape and vision while keeping the patient’s own cornea. A corneal specialist with experience can help determine if CAIRS is the right treatment option for you with early diagnosis and evaluation.

Categories:

Ojas Eye Hospital A Center of Excellence for Contoura Vision, Femto Bladefree Lasik in Mumbai, India.